Monday, November 29, 2010

ABOUT PROFESSOR C HEATHER ASHTON, DM, FRCP



Chrystal Heather Ashton DM, FRCP is Emeritus Professor of Clinical Psycho-pharmacology at the University of Newcastle upon Tyne, England.

Professor Ashton is a graduate of the University of Oxford and obtained a First Class Honours Degree (BA) in Physiology in 1951. She qualified in Medicine (BM, BCh, MA) in 1954 and gained a postgraduate Doctor of Medicine (DM) in 1956. She qualified as MRCP (Member of the Royal College of Physicians, London) in 1958 and was elected FRCP (Fellow of the Royal College of Physicians, London) in 1975. She also became National Health Service Consultant in Clinical Psychopharmacology in 1975 and National Health Service Consultant in Psychiatry in 1994.
She has worked at the University of Newcastle upon Tyne as researcher (Lecturer, Senior Lecturer, Reader and Professor) and clinician since 1965, first in the Department of Pharmacology and latterly in the Department of Psychiatry. Her research has centred, and continues, on the effects of psychotropic drugs (nicotine, cannabis, benzodiazepines, antidepressants and others) on the brain and behaviour in man. Her main clinical work was in running a benzodiazepine withdrawal clinic for 12 years from 1982-1994.

She is at present involved with the North East Council for Addictions (NECA) of which she is former Vice-Chairman of the Executive Committee on which she still serves. She continues to give advice on benzodiazepine problems to counsellors and is patron of the Bristol & District Tranquilliser Project. She was generic expert in the UK benzodiazepine litigation in the 1980s and has been involved with the UK organisation Victims of Tranquillisers (VOT). She has submitted evidence about benzodiazepines to the House of Commons Health Select Committee.

She has published approximately 250 papers in professional journals, books and chapters in books on psychotropic drugs of which over 50 concern benzodiazepines. She has given evidence to various Government committees on tobacco smoking, cannabis and benzodiazepines and has given invited lectures on benzodiazepines in the UK, Australia, Sweden, Switzerland and other countries.



Monday, April 12, 2010

Adverse effects of Benzodiazepines in the elderly.

Excerpt from "The Ashton Manual"

Older people are more sensitive than younger people to the central nervous system depressant effects of benzodiazepines. Benzodiazepines can cause confusion, night wandering, amnesia, ataxia (loss of balance), hangover effects and "pseudodementia" (sometimes wrongly attributed to Alzheimer’s disease) in the elderly and should be avoided wherever possible. Increased sensitivity to benzodiazepines in older people is partly because they metabolise drugs less efficiently than younger people, so that drug effects last longer and drug accumulation readily occurs with regular use. However, even at the same blood concentration, the depressant effects of benzodiazepines are greater in the elderly, possibly because they have fewer brain cells and less reserve brain capacity than younger people.

For these reasons, it is generally advised that, if benzodiazepines are used in the elderly, dosage should be half that recommended for adults, and use (as for adults) should be short-term (2 weeks) only. In addition, benzodiazepines without active metabolites (e.g. oxazepam [Serax], temazepam [Restoril]) are tolerated better than those with slowly eliminated metabolites (e.g. chlordiazepoxide [Librium], nitrazepam [Mogadon]). Equivalent potencies of different benzodiazepines are approximately the same in older as in younger people (Refer to table 1 in the manual).

Thursday, September 3, 2009


"The Ashton Manual"
By Professor Heather Ashton DM, FRCP

Protocol for the treatment of benzodiazepine withdrawal.

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Tranquilizers and Antidepressants: Know the Side Effects


Tranquilizers and Antidepressants: Know the Side Effects is a revised and updated edition to Shirley Trickett's highly successful European and American book Free Yourself from Tranquilizers and Sleeping Pills: A Natural Approach. Her book has a step-by-step program for gradual withdrawal from these addictive substances. It prepares you for possible withdrawal symptoms and explains the natural therapies that effectively address any discomfort you may experience.

Author Shirley Trickett treats you as a complete person, not just a combination of physical symptoms. With clarity and compassion, she offers you the guidance and support necessary to manage your withdrawal. Her constant reassurance - mixed with sound advice on getting support from friends, family and recovery groups - will help you find the strength to persevere towards health and freedom. Above all, her approach is optimistic, always reminding you that you will win through to recovery.

This new updated version has Shirley's added information about possible reasons for prolonged protracted withdrawal, insight into new therapies, updated information on SSRI withdrawal and much much more.

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Thursday, August 27, 2009


The Accidental Addict
by Di Porritt & Di Russell
"The Accidental Addict is and excellent self-help book, offering support, hope and encouragement as well as a full description of benzo symptoms and personal stories of recovery. This book is a very important resource for people having problems discontinuing benzodiazepines."

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